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Two additional midline barriers function with midline lefty1 expression to maintain asymmetric Nodal signaling during left-right axis specification in zebrafish

Left-right (L/R) patterning is crucial for the proper development of all vertebrates and requires asymmetric expression of nodal in the lateral plate mesoderm (LPM). The mechanisms governing asymmetric initiation of nodal have been studied extensively, but because Nodal is a potent activator of its...

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Bibliografiske detaljer
Main Authors: Lenhart, Kari F., Lin, Shin-Yi, Titus, Tom A., Postlethwait, John H., Burdine, Rebecca D.
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177310/
https://ncbi.nlm.nih.gov/pubmed/21937597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.071092
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