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Determination of left/right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer

The nodal gene is expressed on the left side of developing mouse embryos and is implicated in left/right (L-R) axis formation. The transcriptional regulatory regions of nodal have now been investigated by transgenic analysis. A node-specific enhancer was detected in the upstream region (−9.5 to −8.7...

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Autors principals: Adachi, Hitoshi, Saijoh, Yukio, Mochida, Kyoko, Ohishi, Sachiko, Hashiguchi, Hiromi, Hirao, Akiko, Hamada, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC316797/
https://ncbi.nlm.nih.gov/pubmed/10385627
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