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Exploiting Oxytricha trifallax nanochromosomes to screen for non-coding RNA genes

We took advantage of the unusual genomic organization of the ciliate Oxytricha trifallax to screen for eukaryotic non-coding RNA (ncRNA) genes. Ciliates have two types of nuclei: a germ line micronucleus that is usually transcriptionally inactive, and a somatic macronucleus that contains a reduced,...

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Detalhes bibliográficos
Main Authors: Jung, Seolkyoung, Swart, Estienne C., Minx, Patrick J., Magrini, Vincent, Mardis, Elaine R., Landweber, Laura F., Eddy, Sean R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177221/
https://ncbi.nlm.nih.gov/pubmed/21715380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr501
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