Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNA

Within the base excision repair (BER) pathway, the DNA N-glycosylases are responsible for locating and removing the majority of oxidative base damages. Endonuclease III (Nth), formamidopyrimidine DNA glycosylase (Fpg) and endonuclease VIII (Nei) are members of two glycosylase families: the helix–hai...

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Detalhes bibliográficos
Main Authors: Dunn, Andrew R., Kad, Neil M., Nelson, Shane R., Warshaw, David M., Wallace, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177204/
https://ncbi.nlm.nih.gov/pubmed/21666255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr459
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