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DNA slip-outs cause RNA polymerase II arrest in vitro: potential implications for genetic instability
The abnormal number of repeats found in triplet repeat diseases arises from ‘repeat instability’, in which the repetitive section of DNA is subject to a change in copy number. Recent studies implicate transcription in a mechanism for repeat instability proposed to involve RNA polymerase II (RNAPII)...
में बचाया:
| मुख्य लेखकों: | , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177194/ https://ncbi.nlm.nih.gov/pubmed/21666257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr429 |
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