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Rho-kinase inhibition attenuates calcium-induced contraction in β-escin but not Triton X-100 permeabilized rabbit femoral artery

K(+)-depolarization (KCl) of smooth muscle has long been known to cause Ca(2+)-dependent contraction, but only recently has this G protein-coupled receptor (GPCR)-independent stimulus been associated with rhoA kinase (ROCK)-dependent myosin light chain (MLC) phosphatase inhibition and Ca(2+) sensiti...

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Detalhes bibliográficos
Main Authors: Clelland, Lyndsay J., Browne, Brendan M., Alvarez, Silvina M., Miner, Amy S., Ratz, Paul H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177027/
https://ncbi.nlm.nih.gov/pubmed/21706258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10974-011-9253-x
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