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Cocaine increases phosphorylation of MeCP2 in the rat striatum in vivo: a differential role of NMDA receptors
Methyl CpG-binding protein-2 (MeCP2) is a transcriptional regulator that binds to methylated DNA at CpG sites and functions to silence DNA transcription. MeCP2 is subject to the phosphorylation modification at serine 421 (S421), which releases MeCP2 from DNA and thus facilitates gene expression. As...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177009/ https://ncbi.nlm.nih.gov/pubmed/21704097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2011.04.013 |
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