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Short Stat5-Interacting Peptide Derived from Phospholipase C-β3 Inhibits Hematopoietic Cell Proliferation and Myeloid Differentiation

Constitutive activation of the transcription factor Stat5 in hematopoietic stem/progenitor cells leads to various hematopoietic malignancies including myeloproliferative neoplasm (MPN). Our recent study found that phospholipase C (PLC)-β3 is a novel tumor suppressor involved in MPN, lymphoma and oth...

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Detalhes bibliográficos
Main Authors: Yasudo, Hiroki, Ando, Tomoaki, Xiao, Wenbin, Kawakami, Yuko, Kawakami, Toshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176784/
https://ncbi.nlm.nih.gov/pubmed/21949826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024995
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