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Second-generation high-throughput forward genetic screen in mice to isolate subtle behavioral mutants

Forward genetic screens have been highly successful in revealing roles of genes and pathways in complex biological events. Traditionally these screens have focused on isolating mutants with the greatest phenotypic deviance, with the hopes of discovering genes that are central to the biological event...

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Detalhes bibliográficos
Main Authors: Kumar, Vivek, Kim, Kyungin, Joseph, Chryshanthi, Thomas, Lisa C., Hong, Heekyung, Takahashi, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176609/
https://ncbi.nlm.nih.gov/pubmed/21896739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107726108
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