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A critical role for SOCS3 in innate resistance to Toxoplasma gondii
The innate and adaptive immune responses that confer resistance to the intracellular pathogen Toxoplasma gondii critically depend on IL-12 production, which drives interferon-γ (IFN-γ) expression. Certain cytokines can activate STAT3 and limit IL-12 production to prevent infection-associated immune...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3176442/ https://ncbi.nlm.nih.gov/pubmed/21925110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.07.009 |
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