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Subcellular Antigen Location Influences T-Cell Activation during Acute Infection with Toxoplasma gondii

Effective control of the intracellular protozoan parasite Toxoplasma gondii depends on the activation of antigen-specific CD8(+) T-cells that manage acute disease and prevent recrudescence during chronic infection. T-cell activation in turn, requires presentation of parasite antigens by MHC-I molecu...

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Detalhes bibliográficos
Main Authors: Gregg, Beth, Dzierszinski, Florence, Tait, Elia, Jordan, Kimberly A., Hunter, Christopher A., Roos, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145783/
https://ncbi.nlm.nih.gov/pubmed/21829561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022936
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