Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8(+) T cells

The Toxoplasma gondii population consists of multiple strains, defined by genotype and virulence. Previous studies have established that protective immunity to this organism is mediated by IL-12, which drives T cells to produce IFN-γ. Paradoxically, while type I and type II strains of T. gondii both...

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Hlavní autoři: Tait, Elia D., Jordan, Kimberly A., Dupont, Christopher D., Harris, Tajie H., Gregg, Beth, Wilson, Emma H., Pepper, Marion, Dzierszinski, Florence, Roos, David S., Hunter, Christopher A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039871/
https://ncbi.nlm.nih.gov/pubmed/20592284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903450
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