Prion Protein Expression and Functional Importance in Skeletal Muscle

Skeletal muscle expresses prion protein (PrP) that buffers oxidant activity in neurons. AIMS: We hypothesize that PrP deficiency would increase oxidant activity in skeletal muscle and alter redox-sensitive functions, including contraction and glucose uptake. We used real-time polymerase chain reacti...

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Main Authors: Smith, Jeffrey D., Moylan, Jennifer S., Hardin, Brian J., Chambers, Melissa A., Estus, Steven, Telling, Glenn C., Reid, Michael B.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2011
Teme:
Forum Original Research Communications Muscle Fatigue (M.B. Reid and S.K. Powers, Eds.)
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176344/
https://ncbi.nlm.nih.gov/pubmed/21453198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.3945
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