Stretch-stimulated glucose uptake in skeletal muscle is mediated by reactive oxygen species and p38 MAP-kinase

Alternatives to the canonical insulin-stimulated pathway for glucose uptake are exercise- and exogenous reactive oxygen species (ROS)-stimulated glucose uptake. We proposed a model wherein mechanical loading, i.e. stretch, stimulates production of ROS to activate AMP-activated kinase (AMPK) to incre...

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Главные авторы: Chambers, Melissa A, Moylan, Jennifer S, Smith, Jeffrey D, Goodyear, Laurie J, Reid, Michael B
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2009
Предметы:
Skeletal Muscle and Exercise
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727043/
https://ncbi.nlm.nih.gov/pubmed/19403598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.165639
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