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Tumor Necrosis Factor-α and Muc2 Mucin Play Major Roles in Disease Onset and Progression in Dextran Sodium Sulphate-Induced Colitis

The sequential events and the inflammatory mediators that characterize disease onset and progression of ulcerative colitis (UC) are not well known. In this study, we evaluated the early pathologic events in the pathogenesis of colonic ulcers in rats treated with dextran sodium sulfate (DSS). Followi...

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Autori principali: Dharmani, Poonam, Leung, Pearl, Chadee, Kris
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176316/
https://ncbi.nlm.nih.gov/pubmed/21949848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025058
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