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Lipopolysaccharide-induced Notch signaling activation through JNK-dependent pathway regulates inflammatory response
BACKGROUND: Notch and TLR pathways were found to act cooperatively to activate Notch target genes and to increase the production of TLR-induced cytokines in macrophages. However, the mechanism of LPS-induced Notch activation and its role in sepsis still remains unclear. METHODS: We analyzed the expr...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3176188/ https://ncbi.nlm.nih.gov/pubmed/21843347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-18-56 |
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