Lipopolysaccharide-induced Notch signaling activation through JNK-dependent pathway regulates inflammatory response

BACKGROUND: Notch and TLR pathways were found to act cooperatively to activate Notch target genes and to increase the production of TLR-induced cytokines in macrophages. However, the mechanism of LPS-induced Notch activation and its role in sepsis still remains unclear. METHODS: We analyzed the expr...

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Autors principals: Tsao, Po-Nien, Wei, Shu-Chen, Huang, Miao-Tzu, Lee, Ming-Cheng, Chou, Hung-Chieh, Chen, Chien-Yi, Hsieh, Wu-Shiun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176188/
https://ncbi.nlm.nih.gov/pubmed/21843347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-18-56
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