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MCP-1–Activated Monocytes Induce Apoptosis in Human Retinal Pigment Epithelium

PURPOSE. The inflammatory response in age-related macular degeneration (AMD) is characterized by mononuclear leukocyte infiltration of the outer blood–retina barrier formed by the retinal pigment epithelium (RPE). A key mechanistic element in AMD progression is RPE dysfunction and apoptotic cell los...

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Autori principali: Yang, Dongli, Elner, Susan G., Chen, Xun, Field, Matthew G., Petty, Howard R., Elner, Victor M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Association for Research in Vision and Ophthalmology, Inc. 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176077/
https://ncbi.nlm.nih.gov/pubmed/21447688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-7023
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