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Activation of P2X Receptors Induces Apoptosis in Human Retinal Pigment Epithelium

PURPOSE. The retinal pigment epithelium (RPE) is considered a primary site of pathology in age-related macular degeneration (AMD), which is the most prevalent form of irreversible blindness worldwide in the elderly population. Extracellular adenosine triphosphate (ATP) acts as a key signaling molecu...

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Détails bibliographiques
Auteurs principaux: Yang, Dongli, Elner, Susan G., Clark, Andrea J., Hughes, Bret A., Petty, Howard R., Elner, Victor M.
Format: Artigo
Langue:Inglês
Publié: Association for Research in Vision and Ophthalmology, Inc. 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101688/
https://ncbi.nlm.nih.gov/pubmed/21071745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6172
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