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Notch Signaling Modulates MUC16 Biosynthesis in an In Vitro Model of Human Corneal and Conjunctival Epithelial Cell Differentiation

PURPOSE. Notch proteins are a family of transmembrane receptors that coordinate binary cell fate decisions and differentiation in wet-surfaced epithelia. We sought to determine whether Notch signaling contributes to maintaining mucosal homeostasis by modulating the biosynthesis of cell surface-assoc...

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Autores principales: Xiong, Linjie, Woodward, Ashley M., Argüeso, Pablo
Formato: Artigo
Lenguaje:Inglês
Publicado: Association for Research in Vision and Ophthalmology, Inc. 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176047/
https://ncbi.nlm.nih.gov/pubmed/21508102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7196
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