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Cyclic stretch-induced apoptosis in rat annulus fibrosus cells is mediated in part by endoplasmic reticulum stress through nitric oxide production

Various mechanical stresses in vivo induce disc cell apoptosis and intervertebral disc (IVD) degeneration, but the underlying molecular mechanism is not fully known. The aim of this study was to investigate the role of endoplasmic reticulum stress in cyclic stretch-induced apoptosis of rat annulus f...

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Bibliografiske detaljer
Main Authors: Zhang, Yue-Hui, Zhao, Chang-Qing, Jiang, Lei-Sheng, Dai, Li-Yang
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175852/
https://ncbi.nlm.nih.gov/pubmed/21336971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00586-011-1718-5
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