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Synaptically Released Zinc Triggers Metabotropic Signaling via a Zinc-Sensing Receptor in the Hippocampus

Zn(2+) is coreleased with glutamate from mossy fiber terminals and can influence synaptic function. Here, we demonstrate that synaptically released Zn(2+) activates a selective postsynaptic Zn(2+)-sensing receptor (ZnR) in the CA3 region of the hippocampus. ZnR activation induced intracellular relea...

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Detalhes bibliográficos
Main Authors: Besser, Limor, Chorin, Ehud, Sekler, Israel, Silverman, William F., Atkin, Stan, Russell, James T., Hershfinkel, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175799/
https://ncbi.nlm.nih.gov/pubmed/19261885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5093-08.2009
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