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Cystathionine beta synthase gene dose dependent vascular remodeling in murine model of hyperhomocysteinemia
Although children born with severe homocystinurea (i.e. cystathionine beta synthase homozygote knockout, CBS−/−) develop deleterious vascular complications with structural malformation and do not live past teenage, the heterozygote (CBS−/+) lives with apparently normal phenotype. Interestingly, this...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
e-Century Publishing Corporation
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3175747/ https://ncbi.nlm.nih.gov/pubmed/21941612 |
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