Earliest Innate Immune Responses Require Macrophage RelA during Pneumococcal Pneumonia

NF-κB regulates cytokine expression to initiate and control the innate immune response to lung infections. The NF-κB protein RelA is critical for pulmonary host defense during Streptococcus pneumoniae pneumonia, but the cell-specific roles of this transcription factor remain to be determined. We hyp...

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Auteurs principaux: Pittet, Lynnelle A., Quinton, Lee J., Yamamoto, Kazuko, Robson, Bryanne E., Ferrari, J. Daniel, Algül, Hana, Schmid, Roland M., Mizgerd, Joseph P.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2011
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175578/
https://ncbi.nlm.nih.gov/pubmed/21216972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0210OC
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