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2,3,7,8-Tetrachlorodibenzo-p-dioxin–Induced MUC5AC Expression: Aryl Hydrocarbon Receptor-Independent/EGFR/ERK/p38-Dependent SP1-Based Transcription

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a potent environmental toxicant. Epidemiological studies have associated TCDD exposure with the development of chronic obstructive pulmonary disease, which is manifested by mucous/goblet cell hyperplasia. The purpose of this research was to elucidate the...

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Detalhes bibliográficos
Main Authors: Lee, Yong C., Oslund, Karen L., Thai, Philip, Velichko, Sharlene, Fujisawa, Tomoyuki, Duong, Trang, Denison, Michael S., Wu, Reen
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175556/
https://ncbi.nlm.nih.gov/pubmed/20971882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0313OC
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