Coupled Nucleotide and Mucin Hypersecretion from Goblet-Cell Metaplastic Human Airway Epithelium

Adenosine triphosphate (ATP) and its metabolite adenosine regulate airway mucociliary clearance via activation of purinoceptors. In this study, we investigated the contribution of goblet cells to airway epithelial ATP release. Primary human bronchial epithelial (HBE) cultures, typically dominated by...

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Detalhes bibliográficos
Main Authors: Okada, Seiko F., Zhang, Liqun, Kreda, Silvia M., Abdullah, Lubna H., Davis, C. William, Pickles, Raymond J., Lazarowski, Eduardo R., Boucher, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175555/
https://ncbi.nlm.nih.gov/pubmed/20935191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0253OC
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