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Palmitate-Induced Translocation of Caveolin-3 and Endothelial Nitric Oxide Synthase in Cardiomyocytes

PROBLEM STATEMENT: Palmitate is a known cardiac lipotoxin that blunts cardiomyocyte contractile function and induces apoptosis, likely via accumulation of the lipotoxic ceramide. Ceramide is a sphingolipid and localizes to caveolae, which are lined in the inner membrane leaflet by caveolin proteins....

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Détails bibliographiques
Auteurs principaux: Knowles, Catherine J., Dionne, Megan, Cebova, Martina, Pinz, Ilka M.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175373/
https://ncbi.nlm.nih.gov/pubmed/21935356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3844/ojbsci.2011.27.36
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