The angiotensin-converting enzyme inhibitor captopril inhibits poly(ADP-ribose)polymerase activation and exerts beneficial effects in an ovine model of burn and smoke injury

We investigated the effect of the angiotensin converting enzyme (ACE) inhibitor captopril in a clinically relevant ovine model of smoke and burn injury, with special reference to oxidative stress, activation of poly(ADP-ribose) polymerase in the lung and in circulating leukocytes. Female, adult shee...

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Main Authors: Asmussen, Sven, Bartha, Eva, Olah, Gabor, Sbrana, Elena, Rehberg, Sebastian W., Yamamoto, Yusuke, Enkhbaatar, Perenlei, Hawkins, Hal K., Ito, Hiroshi, Cox, Robert A., Traber, Lillian D., Traber, Daniel L., Szabo, Csaba
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175286/
https://ncbi.nlm.nih.gov/pubmed/21701415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318228f614
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