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Misfolded Protein Aggregates: Mechanisms, Structures and Potential for Disease Transmission

Some of the most prevalent human degenerative diseases appear as a result of the misfolding and aggregation of proteins. Compelling evidence suggest that misfolded protein aggregates play an important role in cell dysfunction and tissue damage, leading to the disease. Prion protein (Prion diseases),...

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Detalhes bibliográficos
Main Authors: Moreno-Gonzalez, Ines, Soto, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175247/
https://ncbi.nlm.nih.gov/pubmed/21571086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.04.002
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