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N-Acetylcysteine Increases the Frequency of Bone Marrow Pro-B/Pre-B Cells, but Does Not Reverse Cigarette Smoking-Induced Loss of This Subset

BACKGROUND: We previously showed that mice exposed to cigarette smoke for three weeks exhibit loss of bone marrow B cells at the Pro-B-to-pre-B cell transition, but the reason for this is unclear. The antioxidant N-acetylcysteine (NAC), a glutathione precursor, has been used as a chemopreventive age...

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Bibliografiset tiedot
Päätekijät: Palmer, Victoria L., Kassmeier, Michele D., Willcockson, James, Akhter, Mohammed P., Cullen, Diane M., Swanson, Patrick C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174966/
https://ncbi.nlm.nih.gov/pubmed/21949757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024804
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