Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cells

BACKGROUND: Spinocerebellar ataxia (SCA) refers to a disease entity in which polyglutamine aggregates are over-produced in Purkinje cells (PCs) of the cerebellum as well as other neurons in the central nervous system, and the formation of intracellular polyglutamine aggregates result in the loss of...

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Main Authors: Chang, You-Kang, Chen, Ming-Hsiang, Chiang, Yi-Hung, Chen, Yu-Fan, Ma, Wei-Hsien, Tseng, Chian-You, Soong, Bin-Wen, Ho, Jennifer H, Lee, Oscar K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174876/
https://ncbi.nlm.nih.gov/pubmed/21824437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-18-54
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