Pharmacogenetic angiogenesis profiling for first-line bevacizumab plus oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer

PURPOSE: There is substantial germline genetic variability within angiogenesis pathway genes, thereby causing inter-individual differences in angiogenic capacity and resistance to anti-angiogenesis therapy. We investigated germline polymorphisms in genes involved in VEGF-dependent and –independent a...

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Main Authors: Gerger, Armin, El-Khoueiry, Anthony, Zhang, Wu, Yang, Dongyun, Singh, Harpreet, Bohanes, Pierre, Ning, Yan, Winder, Thomas, LaBonte, Melissa J., Wilson, Peter M., Benhaim, Leonor, Paez, David, El-Khoueiry, Rita, Absenger, Gudrun, Lenz, Heinz-Josef
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174848/
https://ncbi.nlm.nih.gov/pubmed/21791631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1115
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