PARTICIPATION OF TRANSLESION SYNTHESIS DNA POLYMERASES IN THE MAINTENANCE OF CHROMOSOME INTEGRITY IN YEAST SACCHAROMYCES CEREVISIAE

We employed a genetic assay based on illegitimate hybridization of heterothallic Saccharomyces cerevisiae strains (the α-test) to analyze the consequences for genome stability of inactivating translesion synthesis (TLS) DNA polymerases. The α-test is the only assay that measures the frequency of dif...

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Hauptverfasser: Kochenova, O. V., Soshkina, J. V., Stepchenkova, E. I., Inge-Vechtomov, S. G., Shcherbakova, P. V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174683/
https://ncbi.nlm.nih.gov/pubmed/21568839
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