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Single cell analysis reveals similar functional competence of dominant and nondominant CD8 T-cell clonotypes

Immune protection from infectious diseases and cancer is mediated by individual T cells of different clonal origin. Their functions are tightly regulated but not yet fully characterized. Understanding the contribution of each T cell will improve the prediction of immune protection based on laborator...

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Autores principales: Speiser, Daniel E., Wieckowski, Sébastien, Gupta, Bhawna, Iancu, Emanuela M., Baumgaertner, Petra, Baitsch, Lukas, Michielin, Olivier, Romero, Pedro, Rufer, Nathalie
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174610/
https://ncbi.nlm.nih.gov/pubmed/21876175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105419108
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