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Differential radial capillary action of ligand assay for high-throughput detection of protein-metabolite interactions
Interactions of proteins with low-molecular-weight ligands, such as metabolites, cofactors, and allosteric regulators, are important determinants of metabolism, gene regulation, and cellular homeostasis. Pharmaceuticals often target these interactions to interfere with regulatory pathways. We have d...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174574/ https://ncbi.nlm.nih.gov/pubmed/21876132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018949108 |
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