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Differential radial capillary action of ligand assay for high-throughput detection of protein-metabolite interactions

Interactions of proteins with low-molecular-weight ligands, such as metabolites, cofactors, and allosteric regulators, are important determinants of metabolism, gene regulation, and cellular homeostasis. Pharmaceuticals often target these interactions to interfere with regulatory pathways. We have d...

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מידע ביבליוגרפי
Main Authors: Roelofs, Kevin G., Wang, Jingxin, Sintim, Herman O., Lee, Vincent T.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174574/
https://ncbi.nlm.nih.gov/pubmed/21876132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018949108
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