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Inhibition of the protein kinase MK-2 protects podocytes from nephrotic syndrome-related injury

While mitogen-activated protein kinase (MAPK) activation has been implicated in the pathogenesis of various glomerular diseases, including nephrotic syndrome (NS), its specific role in podocyte injury is not known. We hypothesized that MK-2, a downstream substrate of p38 MAPK, mediates the adverse e...

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Main Authors: Pengal, Ruma, Guess, Adam J., Agrawal, Shipra, Manley, Joshua, Ransom, Richard F., Mourey, Robert J., Benndorf, Rainer, Smoyer, William E.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174552/
https://ncbi.nlm.nih.gov/pubmed/21613416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00661.2010
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