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Myeloid differentiation primary response protein 88 blockade upregulates indoleamine 2,3-dioxygenase expression in rheumatoid synovial fibroblasts

Indoleamine 2,3-dioxygenase (IDO) is a key negative regulator of immune responses and has been implicated in tumor tolerance, autoimmune disease and asthma. IDO was detected in the joint synovial tissue in the inflammatory microenvironment of rheumatoid arthritis (RA), but IDO expression in joint sy...

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Hlavní autoři: Park, Mi-Kyung, Oh, Hye-Jwa, Heo, Yang-Mi, Park, Eun-Mi, Cho, Mi-La, Kim, Ho-Youn, Park, Sung-Hwan
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Biochemistry and Molecular Biology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174378/
https://ncbi.nlm.nih.gov/pubmed/21654189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2011.43.8.050
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