Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs

MicroRNAs regulate networks of genes to orchestrate cellular functions. MiR-125b, the vertebrate homologue of the Caenorhabditis elegans microRNA lin-4, has been implicated in the regulation of neural and hematopoietic stem cell homeostasis, analogous to how lin-4 regulates stem cells in C. elegans....

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Main Authors: Le, Minh T. N., Shyh-Chang, Ng, Khaw, Swea Ling, Chin, Lingzi, Teh, Cathleen, Tay, Junliang, O'Day, Elizabeth, Korzh, Vladimir, Yang, Henry, Lal, Ashish, Lieberman, Judy, Lodish, Harvey F., Lim, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174204/
https://ncbi.nlm.nih.gov/pubmed/21935352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002242
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