Unpolarized Release of Vaccinia Virus and HIV Antigen by Colchicine Treatment Enhances Intranasal HIV Antigen Expression and Mucosal Humoral Responses

The induction of a strong mucosal immune response is essential to building successful HIV vaccines. Highly attenuated recombinant HIV vaccinia virus can be administered mucosally, but even high doses of immunization have been found unable to induce strong mucosal antibody responses. In order to solv...

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Bibliografiske detaljer
Main Authors: Zhang, Yan, Yang, Jingyi, Bao, Rong, Chen, Yaoqing, Zhou, Dihan, He, Benxia, Zhong, Maohua, Li, Yaoming, Liu, Fang, Li, Qiaoli, Yang, Yi, Han, Chen, Sun, Ying, Cao, Yuan, Yan, Huimin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174162/
https://ncbi.nlm.nih.gov/pubmed/21935396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024296
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