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Immune Modulation through 4-1BB Enhances SIV Vaccine Protection in Non-Human Primates against SIVmac251 Challenge

Costimulatory molecules play a central role in the development of cellular immunity. Understanding how costimulatory pathways can be directed to positively influence the immune response may be critical for the generation of an effective HIV vaccine. Here, we evaluated the ability of intravenous admi...

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Библиографические подробности
Главные авторы: Hirao, Lauren A., Hokey, David A., Morrow, Matthew P., Jure-Kunkel, Maria N., Weiner, David B.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174159/
https://ncbi.nlm.nih.gov/pubmed/21935390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024250
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