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A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils

During infection, chemokines sequestered on endothelium induce recruitment of circulating leukocytes into the tissue where they chemotax along chemokine gradients toward the afflicted site. The aim of this in vivo study was to determine whether a chemokine gradient was formed intravascularly and inf...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Massena, Sara, Christoffersson, Gustaf, Hjertström, Elina, Zcharia, Eyal, Vlodavsky, Israel, Ausmees, Nora, Rolny, Charlotte, Li, Jin-Ping, Phillipson, Mia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173988/
https://ncbi.nlm.nih.gov/pubmed/20530797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-266072
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