No evidence for clonal selection due to lentiviral integration sites in human induced pluripotent stem cells

Derivation of induced pluripotent stem (iPS) cells requires the expression of defined transcription factors (among Oct3/4, Sox2, Klf4, c-Myc, Nanog and Lin28) in the targeted cells. Lentiviral or standard retroviral gene transfer remains the most robust and commonly used approach. Low reprogramming...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Winkler, Thomas, Cantilena, Amy, Métais, Jean-Yves, Xu, Xiuli, Nguyen, Anh-Dao, Borate, Bhavesh, Antosiewicz-Bourget, Jessica E., Wolfsberg, Tyra G., Thomson, James A., Dunbar, Cynthia E.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173982/
https://ncbi.nlm.nih.gov/pubmed/20166152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.322
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares