Th1 Cytokine-Secreting Recombinant Mycobacterium bovis Bacillus Calmette-Guérin and Prospective Use in Immunotherapy of Bladder Cancer

Intravesical instillation of Mycobacterium bovis bacillus Calmette-Guérin (BCG) has been used for treating bladder cancer for 3 decades. However, BCG therapy is ineffective in approximately 30–40% of cases. Since evidence supports the T helper type 1 (Th1) response to be essential in BCG-induced tum...

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Bibliografiska uppgifter
Huvudupphovsmän: Luo, Yi, Henning, Jonathan, O'Donnell, Michael A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2011
Ämnen:
Review Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173967/
https://ncbi.nlm.nih.gov/pubmed/21941579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/728930
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