An in vivo comparison of bacillus Calmette–Guérin (BCG) and cytokine-secreting BCG vaccines

A recombinant bacillus Calmette–Guérin (BCG) vaccine has been developed, which constitutively secretes interleukin (IL)-2. Groups of deer were immunized with either normal BCG (Pasteur 1173 P2 strain) or recombinant BCG (rBCG/IL-2) and their immune responses were monitored over 3 months. Animals gai...

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Main Authors: Slobbe, L, Lockhart, E, O'Donnell, M A, Mackintosh, C, De Lisle, G, Buchan, G
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 1999
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326794/
https://ncbi.nlm.nih.gov/pubmed/10233736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00702.x
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