Novel approach for interleukin-23 up-regulation in human dendritic cells and the impact on T helper type 17 generation

Interleukin-23 (IL-23) is important for T helper type 17 (Th17) responses and strategies to regulate IL-23 in human dendritic cells (DC) are limited. This study describes a novel means to control IL-23 secretion by conditioning DC with a phosphatidyl inositol 3-kinase inhibitor Wortmannin (WM). Trea...

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Detalhes bibliográficos
Main Authors: Wang, Qunwei, Franks, Hester A, Porte, Joanne, El Refaee, Mohamed, Shah, Suharsh, Crooks, James, Patel, Poulam M, Jackson, Andrew M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173695/
https://ncbi.nlm.nih.gov/pubmed/21718315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03467.x
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