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Increased interleukin-10 production by ASC-deficient CD4(+) T cells impairs bystander T-cell proliferation
Apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) is an important component of the inflammasome, functioning as an adaptor protein that facilitates the recruitment and activation of procaspases that in turn promote the maturation of interleukin-1β (IL-1β) and IL-1...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173692/ https://ncbi.nlm.nih.gov/pubmed/21718313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03462.x |
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