Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing

Aging is a major risk factor for chronic disease in the human population, but there is little human data on gene expression alterations that accompany the process. We examined human peripheral blood leucocyte in-vivo RNA in a large-scale transcriptomic microarray study (subjects aged 30 to 104 years...

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Detalhes bibliográficos
Main Authors: Harries, Lorna W., Hernandez, Dena, Henley, William, Wood, Andrew, Holly, Alice C., Bradley-Smith, Rachel M., Yaghootkar, Hanieh, Dutta, Ambarish, Murray, Anna, Frayling, Timothy M., Guralnik, Jack M., Bandinelli, Stefania, Singleton, Andrew, Ferrucci, Luigi, Melzer, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173580/
https://ncbi.nlm.nih.gov/pubmed/21668623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00726.x
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