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Effects of Imatinib Mesylate (Gleevec) on Human Islet NF-kappaB Activation and Chemokine Production In Vitro

PURPOSE: Imatinib Mesylate (Gleevec) is a drug that potently counteracts diabetes both in humans and in animal models for human diabetes. We have previously reported that this compound in human pancreatic islets stimulates NF-κB signaling and islet cell survival. The aim of this study was to investi...

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Detalhes bibliográficos
Main Authors: Mokhtari, Dariush, Li, Tingting, Lu, Tao, Welsh, Nils
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173488/
https://ncbi.nlm.nih.gov/pubmed/21935477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024831
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