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Invariant NKT cells are required for airway inflammation induced by environmental antigens

Invariant NKT cells (iNKT cells) are a unique subset of T lymphocytes that rapidly carry out effector functions. In this study, we report that a majority of sterile house dust extracts (HDEs) tested contained antigens capable of activating mouse and human iNKT cells. HDEs had adjuvant-like propertie...

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Detalhes bibliográficos
Main Authors: Wingender, Gerhard, Rogers, Paul, Batzer, Glenda, Lee, Myung Steve, Bai, Dong, Pei, Bo, Khurana, Archana, Kronenberg, Mitchell, Horner, Anthony A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173256/
https://ncbi.nlm.nih.gov/pubmed/21624935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102229
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